Gastro-intestinal disturbance is a very common cause of headache. The gastric disturbance which may give rise to headache may depend on organic stomach disease, or may be associated with the many functional disturbances of the stomach and bowels. The gastro-intestinal disturbance which apparently causes headache in some individuals is manifest in others by some other form of nervous or bodily distress. Organic disease of the gastro-intestinal tract probably does not primarily cause headache. The resulting dyspepsia fermentation, constipation and lessened antiseptic action of the stomach secretions are the probable source of an autointoxication, which may result in a disturbance of the nervous apparatus, and headache may be one of the symptom expressions of the toxemia.
In functional disorders of the stomach, like the dyspepsia due to hygienic errors, the neuroses of the stomach associated with general or local nervous disorders, like neurasthenia and tabes dorsalis, and the gastric neuroses manifested
BILLINGS F. HEADACHES OF GASTRO-INTESTINAL DISORDERS.. JAMA. 1899;XXXIII(13):760–762. doi:10.1001/jama.1899.92450650010001c
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