In January, 1894, there was begun in the St. Peter State Hospital a systematic inquiry into the relation between insanity in our women patients and whatever disturbance of function or disease of the generative organs there might be present. In order to accomplish this purpose, a careful record was made of the incidents of the menstrual period in each case; with reference to the amount and character of the discharge, the length of the period, the presence or absence of pain, headache, or general disturbance; and finally as to whether there was any change or exaggeration of the mental disturbance during the period. Then each patient was subjected to a careful physical examination and a record made of the conditions found. In all of the cases where pelvic disease was present and apparent, and in those cases in which there was menstrual disorder, a systematic study of the conditions found,
TOMLINSON HA, BASSETT ME. ASSOCIATION OF PELVIC DISEASES AND INSANITY IN WOMEN, AND THE INFLUENCE OF TREATMENT OF THE LOCAL DISEASE UPON THE MENTAL CONDITION. JAMA. 1899;XXXIII(14):827–831. doi:10.1001/jama.1899.92450660017001e
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