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Article
September 30, 1899

CHOLECYSTITIS.ITS RELATION TO ANGIOCHOLITIS AND CHOLELITHIASIS.

Author Affiliations

BUFFALO, N. Y.

JAMA. 1899;XXXIII(14):831-835. doi:10.1001/jama.1899.92450660021001f
Abstract

In the etiology of cholecystitis, what rôle is played by biliary calculi, trauma, exposure to cold, and what by invasion of the gall-bladder by pathogenic bacteria?

To explain the various painful and obstructive disturbances of the biliary passages by attributing them to gall-stone has been so simple and natural that such pathology went for a long time unchallenged. The suspicion that the process was vastly more complex than we have imagined has long been held, and during the past ten years our knowledge on the subject has so much widened that the pathologic position of the calculus in so-called gall-stone attacks has undergone a radical change. There were series of ascertained facts that were not to be disposed of by the simple statement that gall-stone was present, and for some unknown reason took upon itself to migrate from the gall-bladder. Here are a few of these facts:

  1. In a large

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