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October 21, 1899


JAMA. 1899;XXXIII(17):1046-1047. doi:10.1001/jama.1899.02450690050006

Cytology is the most important, as well as the most fascinating, department of physiology and pathology. Though it is doubtful if we shall ever arrive at a perfect solution of the structure and functions of the cell, since all our means of investigation change its nature and put to flight that subtle something within its substance which we call vitality, our labors have nevertheless been sufficiently rewarded by revelations so startling as to stimulate us to further investigations.

The discovery of the cell as the ultimate unit of organic structure and the confirmation of Virchow's famous dictum, "omnis cellula e cellula," closed two immense gaps in the path of scientific knowledge. Though some doubt has been cast on the importance of the cell form as a factor in organic life, its constant presence, as well as its evolution from pre-existing cells, has never been disputed.

In regard to the minute

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