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Article
October 28, 1899

ACTION OF HEPATIC, RENAL AND OTHER CELLS ON PHENOL AND INDOL, UNDER NORMAL AND PATHOLOGIC CONDITIONS.

JAMA. 1899;XXXIII(18):1106-1107. doi:10.1001/jama.1899.02450700050007
Abstract

Experimentalobservations on the behavior of animal cells toward such substances as indol and phenol have been made by Herter and Wakeman1. Their research was prompted by the interest which is beginning to be felt in the study of the defenses of the organism, to use this familiar phrase, against damage through chemical agencies. Among the problems which arise in connection with this matter are: the determination of the seat of defensive action, whether in the blood or in the cells; the rôle of different kinds of cells on particular chemical agents; and the nature of the chemical changes which may occur. Naturally more interest is connected with the fate of indol and phenol in the organism than with that of wholly foreign substances. Indol and phenol are also recognizable by delicate color reactions, a fact of much practical value in an investigation of this sort. By mixing solutions of

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