Within the past year the bacteriologic diagnosis of typhoid has been enriched by several new methods, as noticed in the several departments of The Journal. That of Piorkowsky, by cultures from loops of the supported feces, using normal urine specially prepared with peptone and gelatin, has been confirmed by others, though as Wittich has shown, some further tests may be necessary to differentiate the colon bacillus.1 More recently, however, Cesaris Demel has found that by using liver bouillon we can have an early means of differentiating the typhoid bacillus, and with the addition of litmus, also eleven other micro-organisms, including the colon and icteroid bacilli, and the cholera vibrio, by reactions characteristic of each2. With these methods, and especially the latter, we seem to have a valuable additional aid in the diagnosis of typhoid, and this with the possibility of detecting the change as early, according to Cesaris
THE DIAGNOSIS OF TYPHOID. JAMA. 1900;XXXIV(3):177. doi:https://doi.org/10.1001/jama.1900.02460030051013
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