The presence of streptococcus pyogenes as a complication or sequel to many of the diseases of infancy or childhood exerts an influence on the course, duration or character of the disease so far as to give rise to new symptoms, utterly at variance with the initial malady. and significant of a dangerous, if not a fatal, result. As an independent affection the streptococci or the staphylococci are found so very frequently that they have given distinctive diseases.
Under the name "septicemia" is presented that complex disease which has for its origin the entrance of either of these microbes into the circulation, and by it is understood a poisoned blood. The term was originally employed by Koch for a condition of microbic blood infection, in which the microbes multiply in the blood, and cause a rapidly fatal disease. The true name of this infection might be termed "strepto-infection" or "strepto-septicemia," or
ROSENTHAL E. TREATMENT OF SEPTIC CONDITIONS IN CHILDREN.. JAMA. 1900;XXXIV(7):405–407. doi:10.1001/jama.1900.24610070021001k
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