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March 17, 1900


JAMA. 1900;XXXIV(11):691-692. doi:10.1001/jama.1900.02460110051007

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The recent demonstration before the New York Academy of Medicine (The Journal, Feb. 24, p. 505), of the results of the year's work in the investigation of the etiology of cancer at the New York State Cancer Laboratory in Buffalo, introduces the very latest phase—what may be called an American phase—of this very interesting subject. The results of the studies of the laboratory seem to point to the conclusion that a yeast is the microorganism whose growth in the tissues somehow sets up sufficient irritation to cause the irresponsible overgrowth of cells that we know as a malignant tumor. This yeast is, at least as far as our present knowledge goes, the ordinary saccharomyces, so familiarly known because of its spontaneous development in sugar solutions whenever they are exposed to the air. Its seeds exist in the atmosphere the world over.

It is somewhat of a shock to the ordinary

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