Generisch1 describes the bacteriologic investigation of suspicious water in a local epidemic of typhoid fever, in a Hungarian town by the name of Pécs. The facts are briefly these: After a heavy rain storm, in December, 1898, the water from two reservoirs became turbid and stinking; an epidemic of typhoid fever broke out suddenly in the parts that received their water from these sources; 209 cases developed, with 28 deaths; the suspected reservoirs were demolished and three weeks later the epidemic subsided. Generisch was sent from Budapest to examine the water bacteriologically. He made a large number of plate cultures on which grew something like 157 colonies suspiciously like those of bacillus typhosus; of these 103 resembled typhoid bacilli in gelatin stabs, and of the 103 stained preparations and hanging drops corresponded to typhoid bacilli in 61 instances; inoculations on potato, of the 61 growths, gave cultures like typhoid
DEMONSTRATION OF TYPHOID BACILLI IN DRINKING WATER, CAUSING AN EPIDEMIC OF TYPHOID FEVER. JAMA. 1900;XXXIV(13):822–823. doi:10.1001/jama.1900.02460130054017
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