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April 14, 1900


Author Affiliations


JAMA. 1900;XXXIV(15):906. doi:10.1001/jama.1900.24610150012001g

Three years ago I reported my impressions of the efficacy of antistreptococcus serum based on experience with 5 or 6 cases. In some of these the presence of the streptococci in the wound-discharges had been demonstrated, and in others staphylococci had been found both in the discharges and in the blood on culture. At that time my conclusion was that the serum rarely if ever did harm, and that in desperate cases the patient should be given the benefit of this treatment in connection with other and better known therapeutic measures. Further acquaintance with the subject has not caused me to modify the views I then held, though the percentage of recoveries due, apparently, to the employment of the remedy has not been encouraging.

Several cases in which there were clinical symptoms of the severest type of sepsis seemed to yield to the serum treatment instituted before it was possible

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