In a paper before the Academy of Medicine March 1, 1900, I gave a brief résumé of the cases of sarcoma thus far treated by myself with injections of mixed toxins. In the few minutes alloted to me this evening it will scarcely be possible to do more than give a short abstract of these results. My recent experience has given me no reason to change the conclusions already expressed in earlier papers; I still find the round-celled sarcoma is much less susceptible to the inhibitory action of the toxins than the spindle-celled, and the melanotic is even less affected. In regard to the method of preparing the toxins, the technique and administration, I have nothing new to add. The preparation which I still believe to be the best is the mixed unfiltered toxins of erysipelas and bacillus prodigiosus made from cultures grown together in the same bouillon and sterilized
COLEY WB. THE MIXED TOXINS OF ERYSIPELAS AND BACILLUS PRODIGIOSUS IN THE TREATMENT OF SARCOMA. JAMA. 1900;XXXIV(15):906–908. doi:10.1001/jama.1900.24610150012001h
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