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April 21, 1900


JAMA. 1900;XXXIV(16):1010. doi:10.1001/jama.1900.02460160052016

According to current conceptions on the subject of tuberculosis, any plan of treatment, to be successful, must be directed to the improvement of the general nutrition, to the stimulation of those forces, as yet unknown, capable of repelling the invasion and of resisting the activity of the tubercle bacillus, of neutralizing its effects and of repairing the injury it has accomplished. The mere presence of this bacillus does not constitute the disease, which rather represents the reaction between the micro-organism and the tissues that have become susceptible to its attack by reason of depraved nutrition or other expression of impaired immunity. Many remedies have been proposed for the treatment of tuberculosis, but none has a specific influence, if we except tuberculin, and this has proved itself a two-edged sword. Among the drugs that have been recommended in the treatment of tuberculosis and from which encouraging results have been reported is