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April 28, 1900


JAMA. 1900;XXXIV(17):1075. doi:10.1001/jama.1900.02460170055013

While it has been shown that many bacterial germs, as well as some higher organisms, will resist almost any known or applicable degree of cold and retain their vitality after subjection to the temperature of liquid air, it is also true that low temperatures do have a certain restrictive action on their growth. Even more than this, it appears to be also true that the ordinary cold of winter temperature has a destructive influence oncertain pathogenic germs. Thus, while the pollution of ice used for dietary purposes has been known to cause intestinal disturbance, it appears that there is in the literature no record of any epidemic of typhoid fever having been caused this way. Sedgwick and Winslow1 have investigated the action of freezing on Eberth's bacillus, with special reference to this point. While it is known that cultures of this germ are not sterilized by freezing, the question