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May 19, 1900


JAMA. 1900;XXXIV(20):1268. doi:10.1001/jama.1900.02460200054013

The use of tuberculin in the human subject, either for therapeutic or diagnostic purposes, has as yet no recognized standing with the profession, and there is a very wide-spread suspicion that it may sometimes revive latent foci and thus arouse at once, what is for the time, at least, a harmless condition into a dangerous state of disease. It has, however, its advocates, and among them we may include, in a somewhat qualified sense, Dr. Edward R. Baldwin,1 Saranac Lake, N. Y., who thinks that clinical experience, as well as experiments on animals, shows that it "can favorably influence a pure localized pulmonary tuberculosis and lupus in a well-nourished afebrile patient," but does not, he says, presume to decide whether tuberculins of any sort should be favored for limited therapeutic employment in the light of our present knowledge. This is, indeed, a very qualified endorsement, but it leaves the