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May 10, 1965

Brain Scans in Diagnosis of Cerebrovascular Disease: Scanning With Chlormerodrin Hg 203

Author Affiliations

From the departments of medicine (Drs. Waxman and Ziegler) and radiology (Dr. Rubin), Menorah Medical Center, Kansas City, Mo. Drs. Waxman and Ziegler are now at the University of Kansas Medical Center, Lawrence, Kan.

JAMA. 1965;192(6):453-456. doi:10.1001/jama.1965.03080190019005

Twenty-seven patients were studied with a total of 30 brain scans done with chlormerodrin Hg 203 at variable periods of time after cerebrovascular accidents. Infarctions, hemorrhages (both intracerebral and subdural), and insufficiencies were represented in this study. A large percentage of very-high-uptake concentration was demonstrated, except in insufficiencies and in a scan of a lesion of the posterior fossa. Increased uptake was obtained as late as 53 days postinfarction. It is emphasized that in this study the uptake obtained in patients with cerebrovascular disease could not be differentiated from tumors on the basis of scanning alone. Some speculation as to the mechanism of this increased uptake is presented.