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May 10, 1965

Iodide Fever

JAMA. 1965;192(6):571-572. doi:10.1001/jama.1965.03080190137034

IODISM is a term applied to the symptoms and signs manifested by a patient who is sensitive to iodides. Alexander1 lists skin eruptions, fever, coryza, conjunctivitis, and lymphadenopathy as the most common findings. To this list should be added the more rare symptoms of parotid gland swelling2 and myxedema3. Beckman4 states that "fever sometimes accompanies the other symptoms but fever as the sole manifestation of iodism... must be a rare occurrence." The following case history is reported because it represents just such a rare occurrence.

Report of a Case  A 65-year-old white man (DVAH A-074), was admitted to the Denver VA Hospital in November 1962, with a three-week history of fever, chills, nocturia, and dysuria. On the day prior to admission, chloramphenicol therapy was begun. There were several prior hospitalizations because of symptoms referrable to chronic bronchitis and prostatism. Physical examination revealed an increased anterioposterior diameter

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