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Furthernd growing evidence of a second genetic system and its possible role in the initiation of cancer is being reported by a woman scientist at the University of Pennsylvania.
The findings include:
Her report three years ago of seeing deoxyribonucleic acid (DNA) in animal cell mitochondria, an observation also made in several other laboratories.
Biochemical experiments, since confirmed by others, showing that the DNA was truly that of mitochondria and not nuclear contamination.
Systematic studies which indicate that DNA "is an integral part of most and probably all mitochondria."
Evidence that DNA fibers are twice to several times more concentrated in undifferentiated or rapidly dividing cells.
Frequent observation in ascites tumor cells of atypical DNA fibrils intimately associated with a globular body in structurally damaged mitochondria.
Husband and Wife Team
The investigator is Margit M. K. Nass, PhD, of the School of Medicine's Department
New Clues to a Second Genetic System. JAMA. 1965;192(10):33–34. doi:10.1001/jama.1965.03080230143051
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