To determine whether interpretations of radioisotope renograms by qualitative visual inspection were reproducible, a total of 60 randomly assembled renograms, including those of 13 patients with proved unilateral renal hypertension, were subjected to reinterpretation by the initial observer. Fifty-six of the interpretations were in complete agreement. All 13 cases of renovascular hypertension were correctly identified both times. When two quantitative methods of interpretation were applied to renograms of the group with unilateral renal hypertension, diagnostic accuracy was significantly decreased.
Koplowitz JM, Mitchell JF, Blahd WH. The Radioisotope Renogram: A Comparison of Qualitative and Quantitative Interpretation. JAMA. 1965;192(12):1032–1034. doi:10.1001/jama.1965.03080250010002
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