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July 26, 1965

Cervical Neoplasia

JAMA. 1965;193(4):320-321. doi:10.1001/jama.1965.03090040064024

To the Editor:—  Because our initial results with the irrigation smear method were unsatisfactory, we asked Dr. Davis and Miss Palm for help and advice. At our laboratory for two days, they personally prepared a number of smears and, with our chief technician and ourselves, screened them. Miss Palm's screening results of a group of unlabelled smears, which included all our histologically confirmed carcinomas in situ, did not differ appreciably from our own. Since the pipettes were procured from Dr. Davis' supplier, the majority filled with fixative in Dr. Davis' laboratory, and all simply handed to the patient with a copy of Dr. Davis' instruction sheet, it is difficult to detect a lapse in procurement. Because of these visits we felt obliged to acknowledge the assistance received from Dr. Davis' laboratory.It is our opinion that a well-prepared cytological specimen, obtained by os aspiration and scraping with a wooden spatula,