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Article
July 26, 1965

Thrombophlebitis Treated With Dextran

JAMA. 1965;193(4):322. doi:10.1001/jama.1965.03090040066027

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Abstract

To the Editor:—  The controversy over use of dextran in thrombophlebitis (JAMA192:426 [May 3] 1965) gives me the opportunity to state that I have tried it on a number of occasions in thrombophlebitis and have been most impressed with its effectiveness. I will continue to use the dextran in preference to sodium heparin or sodium warfarin having seen a number of poor responses, or lack of response of any kind, to sodium heparin alone or sodium heparin and sodium warfarin.One patient who did not respond to anticoagulants and had a progression of the disease, had a dramatic response to dextran. Unfortunately it could not be continued beyond the two days of therapy because of some reaction to the dextran, which occasionally does give allergic reaction.

Generic and Trade Names of Drugs  Sodium heparin—Heparin Sodium, Liquaemin Sodium.Sodium warfarin—Coumadin Sodium, Panwarfin, Prothromadin.Dextran—Dextran, Epandex, Gentran.

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