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September 27, 1965

Which Method Is Better Able to Cure Positive Pelvic Lymph Nodes?

JAMA. 1965;193(13):1104. doi:10.1001/jama.1965.03090130032008

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A unique opportunity to study pelvic lymph nodes in patients with carcinoma of the cervix, who were staged in the same department and treated at random, either with surgery or with irradiation, arose in the Department of Obstetrics and Gynecology and in the Department of Radiotherapy of the Columbia Presbyterian Medical Center, New York. Before describing our experience I have to outline, in short, the treatment approach and protocol which has given us the background for this study.

An attempt has been made to evaluate the results of surgery and irradiation in the treatment of carcinoma of the cervix in the same institution. According to treatment protocol,5 all patients with cancer of the cervix, stages I, II, and, if feasible, III, would be divided into two groups. Group A was treated surgically with a radical hysterectomy and lymph node dissection, while group B was treated with radium followed by

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