This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables.
Emphysema can be defined only in morphologic terms, according to E. Osborne Coates, MD, Division of Pulmonary Diseases, Henry Ford Hospital, Detroit.
The amount of actual destruction of lung tissue is the criterion. But emphysema is only one of three conditions which may produce diffuse airway obstruction, the others being bronchial asthma and chronic bronchitis. Clinical observation cannot clearly define morphologic emphysema, Dr. Coates noted. All that can be said is that the person has chronic obstructive lung disease —with symptoms and signs of emphysema or bronchitis or asthma. Each condition overlaps the others.
Both emphysema and asthma are characterized by shortness of breath on exertion; bronchitis consists of chronic cough productive of sputum. Emphysema, clinically, produces shortness of breath on exertion, usually occurs in men over 40 years of age, and may or may not be accompanied by cough and sputum. Bronchitis can do the same without necessarily destroying
Emphysema: Several Factors May Cloud Diagnosis. JAMA. 1965;193(13):24–32. doi:10.1001/jama.1965.03090130076038
Customize your JAMA Network experience by selecting one or more topics from the list below.
Create a personal account or sign in to: