Dr. Joseph T. Ferrucci, Jr.: A 70-year-old white man was first seen three years ago complaining of progressive soreness and swelling of his tongue, of at least two years' duration. He gave a long history of pipe smoking. A Hinton test gave positive results. There was a lesion diffusely infiltrating the dorsum of the tongue without fixation to the floor of the mouth. Only the very tip of the tongue anteriorly, the left lateral margin, and the volume behind the circumvallate papillae were spared. The tonsilingual folds throughout were clear. There was no evidence of metastatic disease. Biopsy showed squamous-cell carcinoma.
Dr. Milford D. Schulz: What does syphilitic glossitis mean as far as your treatment plan is concerned, Dr. Wang?Dr. C. C. Wang: A small carcinoma associated with syphilitic glossitis should be treated by excision rather than radiotherapy. A second lesion tends to develop in these patients. In
Ware RG. Treatment of Carcinoma of the Tongue. JAMA. 1965;194(3):288–289. doi:10.1001/jama.1965.03090160066017
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