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November 8, 1965

Treatment of Keloids

JAMA. 1965;194(6):682. doi:10.1001/jama.1965.03090190104045

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To the Editor:—  In The Journal (193:325, 1965) there was an inquiry about a keloid scar developing on the neck, following excision of a large intradermal nevus.Louis T. Byars, MD, discussing therapy, mentioned Maguire's treatment of a large and severe keloid with triamcinolone acetonide aqueous suspension, injected intralesionally, with good improvement (192:325, 1965).If surgical removal of the keloid is not feasible, the end result is usually not too satisfactory cosmetically even with intralesional or sublesional injections of triamcinolone suspension, which seems to be the best available therapy. But if surgical removal of the keloid is feasible, then the following simple technique usually prevents the formation of postsurgical keloid: The keloid is excised with use of local anesthesia, to which triamcinolone acetonide aqueous suspension is added. After excision, weekly local subdermal injections are given (Derm Dig3:49-58, 1964).

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