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December 27, 1965

Visceral Larva Migrans and Peripheral Retinitis

Author Affiliations

From the Francis I. Proctor Foundation for Research in Ophthalmology and the Department of Ophthalmology, University of California, San Francisco Medical Center.

JAMA. 1965;194(13):1345-1347. doi:10.1001/jama.1965.03090260005001

Ocular nematodiasis due to Toxocara canis occurred in a girl 6 years of age who had no history of contact with kittens or puppies, no history of an illness suggesting visceral larva migrans, and no eosinophilia. The left-eye inflammation was observed for over a year and changed very little. It was characterized by a heavy cellular anterior vitreous-body exudate, a large gray mass of exudate in the lower region of the ciliary body, ora serrata, and peripheral retina, and macular and optic-disk edema. Previous surgery had been done for a patent ductus arteriosus. Following the surgery, the patient had cyanosis, and she died about 18 months later of pulmonary hypertension. The eyes were obtained at autopsy, and the right eye was found to be normal. Examination of the left eye showed a larva morphologically identical with T canis within the lower peripheral retinal tissues.