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In the topic of anticoagulant therapy, uncritical and overly enthusiastic appraisals have often diluted the worthwhile contributions of two generations of investigators. Dr. Vigran has succeeded in distinguishing between the good and the poor literature on anticoagulants. He has divided his book into 13 chapters, which include such areas as blood coagulation; thrombosis, embolism, and atherosclerosis; the chemistry and pharmacology of anticoagulant drugs; contraindications to use; and laboratory controls. He goes on with detailed consideration of various forms of vascular disease, as well as the complications of treatment.
Each chapter he introduces with a biographical sketch of a man whose efforts have paced the progress that has been made. This provides a design which might well be copied by other authors of similar reviews.
The volume contains a well-annotated documentation of the present status of anticoagulant therapy and provides an excellent readable summary of its indications. If there is any
Harrington WJ. Clinical Anticoagulant Therapy. JAMA. 1965;194(13):1393. doi:10.1001/jama.1965.03090260053027
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