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Article
December 27, 1965

Dyes May Make Laser Tumor-Selective

JAMA. 1965;194(13):26-27. doi:10.1001/jama.1965.03090260070036

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Abstract

Use of high energy lasers may make it possible to treat many noninflammatory benign skin lesions rapidly and safely without undesirable scarring, a report at the meeting of the American Academy of Dermatology indicates.

Moreover, two investigators from Cincinnati suggested that the laser may be able to destroy only cancer cells if dyes can be injected into and selectively taken up by nonpigmented tumors.

Robert G. Wilson, MD, and Leon Goldman, MD, Department of Dermatology, College of Medicine, University of Cincinnati, told The Journal of preliminary clinical research in which dyes such as methylene blue, Evan's blue, India ink, and cosmetic black were injected into tumors of 20 patients with cancer. These dyes were used for 13 other patients with light-colored benign lesions such as senile keratoses or precancerous lesions and warts.

"The laser has shown a selectivity to light by color, but not a selectivity to cancer cells per

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