GENERALLY THOUGHT to be a protozoan, Pneumocystis carinii has been known for many decades to be the cause of a specific infection of the lung, P carinii pneumonitis. In Europe, P carinii pneumonitis is known to occur predominantly in debilitated and premature infants six weeks to a few months of age, and has been encountered primarily in epidemics in nurseries, resulting in many deaths.1,2 Deamer and Zollinger3 brought this condition to the attention of North American physicians in 1953. In 1956, Gagne and Hould4 presented the first three cases from Canada and since then, an increasingly large number of cases have been recognized in the North American continent. The condition had not been reported in the Far East until 1959, when Lim5 recorded an epidemic of 30 cases in infants occurring in a Korean orphanage. In 1960, Lim and Moon6 presented epidemiologic and clinical studies
Hyun BH, Varga CF, Thalheimer LJ. Pneumocystis carinii Pneumonitis Occurring in an Adopted Korean Infant. JAMA. 1966;195(9):784–786. doi:10.1001/jama.1966.03100090118034
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