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April 4, 1966

Spontaneous Closure of an Atrial Septal Defect

Author Affiliations

From the Department of Pediatrics, Wayne State University School of Medicine, and the Cardiovascular Laboratory. Children's Hospital of Michigan, Detroit.

JAMA. 1966;196(1):17-19. doi:10.1001/jama.1966.03100140071018

Serial hemodynamic and angiocardiographic studies demonstrated the spontaneous closure of an atrial septal defect in a 3-year-9-month-old white boy, the presence of which was confirmed in the second year of life. A possible myocarditis in the first year of life was considered to be potentially instrumental in the closure of this defect. Although similar observations have been made by others, to our knowledge this is the first such case, particularly at this age, reported in the literature.