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May 16, 1966

Sequel to Hyaline Membrane Disease?

JAMA. 1966;196(7):39. doi:10.1001/jama.1966.03100200021008

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A chronic condition, developing in infants who survive hyaline membrane disease and sufficiently different to suggest a separate disease, has been described by California investigators.

They reported on 20 deaths among 40 premature infants critically ill with respiratory distress syndrome (hyaline membrane disease). Twelve died in the first week, three in the first month, and the remaining five survived one or more months to a maximum of 11 months.

The study was done by Robert C. Rosan, MD, assistant professor of pathology; David Y. Porter, MD, chief resident in pathology, and William H. Northway Jr., MD, instructor in radiology, all of Stanford University School of Medicine. The patients had been clinically treated under the supervision of Marshall Klaus, MD.

37 Hours  Discussing their work at the Federation of American Societies for Experimental Biology, Dr. Rosan said all 20 infants studied, and all but one of the original 40, were treated

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