[Skip to Content]
[Skip to Content Landing]
July 4, 1966

An Agent for Stimulating Pigmentation or Tolerance to SunlightTrioxsalen (Trisoralen)

JAMA. 1966;197(1):43. doi:10.1001/jama.1966.03110010095023

Trioxsalen is used to stimulate repigmentation of vitiliginous areas upon exposure to sun or ultraviolet light, and to enhance pigment formation in fair-skinned persons. The dosage of this drug and exposure to light must be carefully regulated to prevent burning. No other photosensitizing agents should be given to patients receiving trioxsalen, and the drug is contraindicated in disease associated with photosensitivity.