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August 8, 1966

The Dangers of LSD: Analysis of Seven Months' Experience in a University Hospital's Psychiatric Service

JAMA. 1966;197(6):389-392. doi:10.1001/jama.1966.03110060063015

The symptoms, diagnostic categories, and general characteristics of patients in 70 cases of adverse reactions to lysergic acid diethylamide tartrate (LSD) are varied. Psychiatric side effects ranged from depressive reaction to psychotic states. In all cases, LSD ingestion occurred separately and apart from medical-experimental and psychiatric-therapeutic models of LSD usage. Findings based on these cases and from observations made on LSD users in the community indicate that widespread use of LSD is a cause for concern.