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August 15, 1966

Bladder Decompensation Correlates With Diabetic Neuropathy

JAMA. 1966;197(7):39. doi:10.1001/jama.1966.03110070025009

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The increased frequency of renal infection seen in the patient with diabetes may be due to the progressive decompensation of the neurogenically involved bladder, two investigators suggest.

In a report to the annual meeting of the American Diabetes Association, Max Ellenberg, MD, and Herbert Weber, MD, Departments of Medicine and Urology, Mount Sinai Hospital, New York City, said they found clear, objective evidence of neurogenic bladder involvement in 30 of 36 patients with diabetic neuropathy.

There were no bladder abnormalities found in the non-diabetic controls, nor in a group of patients with diabetes and without neuropathy.

These patients were studied in an attempt to define the initial manifestations of bladder dysfunction in patients with diabetes.

"The typical diabetic patient with neuropathy and asymptomatic incipient bladder involvement has an abnormal cystometrogram and cystogram but no abnormal residual urine," Dr. Ellenberg said. "There is no growth on culture of the bladder urine;