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October 24, 1966

Transplantation Meets New Barriers

JAMA. 1966;198(4):40. doi:10.1001/jama.1966.03110170022008

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The French clinician who seven years ago performed the first kidney transplant between nonidentical twins now assesses the field he helped found with a mixed prognosis.

Transplantation Reviewed  "If I had to tell you what 1966 represents in renal transplantation, I would have to say it is the time when hope roughly equals the burden of concern," Professor M. Jean Hamburger says.Using his own clinical and laboratory experience as a reference base, the University of Paris surgeon recently reviewed transplantation in an Illinois Kidney Foundation symposium.A number of unanticipated factors tend to cloud the still optimistic demeanor of clinical transplantation, Dr. Hamburger explained.Among them:

  • Evidence that chronic disease may progress for many years in the transplanted kidney,

  • Dangers created by immunosuppressive techniques,

  • Doubts as to the effectiveness of donor selection procedures.

Thirty-nine of the 61 patients who have received kidney transplants in Paris survived