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January 9, 1967


JAMA. 1967;199(2):31-42. doi:10.1001/jama.1967.03120020013005

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The Public Health Service has doubled the recommended interval between tetanus booster shots to ten years.

In recent years, the most frequently heard recommendation in the US, including that of the PHS for international travel, has been maintenance doses every five years.

Some physicians administer the toxoid booster at lesser intervals, annually in some cases.

Members of the AMA's Council on Environmental and Public Health are among those considering the matter of maintenance dose interval in terms of protection levels and possible reactions. Their recommendation is expected in a few weeks.

Immunization Symposium  During a symposium on immunization convened by the Council in cooperation with the National Communicable Disease Center, Atlanta, Ga, Geoffrey Edsall, MD, spoke of the ten-year interval.Dr. Edsall, superintendent of the Institute of Laboratories, Massachusetts Department of Public Health, said that several recent studies have shown primary tetanus immunization, with or without boosters, creates immune response