[Skip to Content]
[Skip to Content Landing]
February 6, 1967

Intestinal Infarction in Shock With Survival After Resection: Relation of the Intestinal Lesion to Shock With High Cardiac Output

Author Affiliations

From the Department of Surgical Research, Division of Surgery, Hektoen Institute for Medical Research of the Cook County Hospital, Chicago.

JAMA. 1967;199(6):422-425. doi:10.1001/jama.1967.03120060120028

INTESTINAL necrosis has been found infrequently at autopsy in patients dying of shock from hemorrhage, trauma, and sepsis.1 However, the entity of acute hemorrhagic necrosis of the intestine following low flow states associated with cardiovascular disease is well recognized, and its pathology has been described by many observers.2-9 In four recently reported autopsy series, representing a total of 240 cases of acute nonocclusive intestinal necrosis, at least 150 patients had evidence of congestive heart failure4-7; the other patients had various types of cardiovascular disease, the most frequent being generalized atherosclerosis. In several cases, infection was the primary etiologic factor. Very few patients were in the younger age group. In no instance did this lesion result from welldocumented acute uncomplicated septic or hemorrhagic shock which was not treated with vasopressors.4-7 Musa5 concluded from his study that the lesion did not occur as a result of shock