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February 6, 1967

Idiopathic Hypertrophic Osteoarthropathy, With Dysproteinemia

JAMA. 1967;199(6):434-435. doi:10.1001/jama.1967.03120060132038

To the Editor:—  Idiopathic hypertrophic osteoarthropathy is a rare disease of young men, first described in 1935 by Touraine, Solente, and Golé.1 It is characterized by clubbing of the fingers, periosteal new bone formation involving especially the long bones, and pachydermoperiostosis plicata. Although swelling and pain of the joints and dysproteinemia were not part of the original syndrome, they have been noted in connection with periosteal hyperostosis.2

Report of a Case:—  A 28-year-old white man was admitted to the Louis A. Weiss Memorial Hospital on April 17, 1966, because of scrotal swelling, arthralgia, and fever. The scrotal swelling followed trauma, and within 96 hours the patient became acutely ill with fever, chills, and markedly swollen painful joints.The history revealed that he had been bedridden for several years at 7 years of age because of generalized "arthritis"; he had been told he had "rheumatic fever." There were