[Skip to Navigation]
February 13, 1967

Peripheral Neuropathy And Tetanus Toxoid

Author Affiliations

Columbus, Ohio

JAMA. 1967;199(7):507. doi:10.1001/jama.1967.03120070119029

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables.


To the Editor:—  In the Clinical Notes (198:1030, 1966), peripheral neuropathy following tetanus toxoid administration was first reported. While it is quite apparent that there was an allergic reaction, it is most probable, if not certain, that the injection was in the vicinity of the radial nerve. Naturally, one would have to see the location of the needle insertion. However, in the posterior aspect of the deltoid muscle, in its lower section, a deep injection could involve the radial nerve, and in the lateral aspect of the arm, if the needle is sufficiently long and goes posteriorly, the material will be injected in the vicinity of the radial nerve.Since the allergic plexitis (if one would call it that) involves the terminal branches of the brachial plexus, it is inconceivable that only a single nerve could be affected, particularly when this nerve is not usually affected in other forms