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February 13, 1967

Peripheral Neuropathy And Tetanus Toxoid

Author Affiliations


JAMA. 1967;199(7):507. doi:10.1001/jama.1967.03120070119030

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To the Editor:—  Dr. Johnson's contention that the reported neuropathy was an injection palsy received consideration but was not favored because it failed to explain the associated constitutional phenomena such as fever, edema of the involved member, and rash and petechiae in parts of the body remote from the injection site. He is also presupposing that a deep injection was given with a long needle in the posterior aspect of the lower portion of the deltoid muscle. While it is impossible to accurately identify the injection site, it has been determined that a 2.5-cc disposable syringe with a 26 gauge 5/8-inch needle was used for the injection. It was our feeling from previous experience that a palsy due to an injection would follow the administration of the material within a reasonable period of time. Such a temporal relationship is lacking in this case.We have had numerous comments, explanations, and