[Skip to Content]
[Skip to Content Landing]
February 20, 1967

Ultrastructural Aspects of Disease

JAMA. 1967;199(8):591. doi:10.1001/jama.1967.03120080125038

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables.


The main purpose of this book is to depict the changes in fine structure found in disease. This difficult aim Dr. King has attempted within the remarkably short confines of 279 pages, including 97 plates. The 308 illustrations making up the plates comprise contributions from 173 investigators. In addition to an introduction relating some of the concepts of modern biology and pathology, there are 15 chapters. The first three considers cell structure, cell injury, and cell response; the remaining 12 cover a corresponding number of systems. Each chapter has an introductory series of statements about general pathologic processes or specific diseases, followed by several plates illustrating some of these changes.

It is plainly impossible to cover comprehensively, in so little space, such a complex and heterogeneous mass of material. The result is a staccato presentation of some highlights and of some important concepts of disease. Of necessity, many of the