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For the conscientious surgeon faced with responsibility for the care of patients with advanced carcinoma of the breast, current prospects are bewildering indeed. He can with some candor tell his patient's family that "much more can be done" than ever before; he can quite honestly hold out the hope that if the proper treatment is selected, she has a likelihood as great as 40% (according to some series) of enjoying a prolonged (1-4 yr) remission from her disease; he can reassure her relatives that during these precious years the young patient (average age 55) rearing a family and with children in school or college, can continue to give them the maternal guidance they want and need; but he can never remove from his own mind the fact that even with these great advances in endocrine method, no one has ever been saved from ultimate destruction by this common and devastating
DISCRIMINATING AMONG DISCRIMINANTS IN ADVANCED BREAST CANCER. JAMA. 1963;184(4):306. doi:10.1001/jama.1963.03700170098013
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