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The long-awaited second edition of Harold Wolff's monograph on headache was completed and sent to the publisher only a few weeks before his untimely death on Feb 21, 1962. The first edition (1948) had marked a milestone in our understanding of a most common and important malady. Previous to the publication of the book, headache was regarded as a troublesome accompaniment of a great number of diseases and abnormalities; however, the mechanisms underlying its development were ill understood. Migraine, because of its high incidence and dramatic prodromes, previously had received extensive scrutiny, but diverse and contradictory ideas were still entertained concerning both its nature and causes. Of all men in medicine, Harold Wolff contributed most to the study of headache and to the clarification of its true significance. His monograph was especially valuable because of its circumstantial account of the remarkable observations which he and his associates had made, over
Barr DP. Headache and other head pain. JAMA. 1963;184(8):665. doi:10.1001/jama.1963.03700210099026
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