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June 15, 1963

Abscess of the Brain in a Patient with Ventricular Septal Defect: Reversal of Blood Flow and Calcification of the Pulmonary Artery

Author Affiliations

New York

From the Department of Pathology, Albert Einstein College of Medicine, Yeshiva University.

JAMA. 1963;184(11):896-898. doi:10.1001/jama.1963.73700240021019b

CALCIFICATION of the pulmonary artery of a patient suffering from enlargement of the right ventricle and main pulmonary arteries has been considered indicative of the presence of a patent ductus arteriosus with right-to-left shunt.1 In the case reported here, calcification of the pulmonary artery with reversal of blood flow was found to be associated with a defect of the membranous portion of the interventricular septum and closed ductus in a patient with an abscess of the brain.

Report of a Case  A 49-yr-old female was admitted to the Bronx Municipal Hospital Center on July 5, 1961, because of vomiting, headache, and unresponsive and bizarre behavior of 1 day's duration. Two weeks prior to this admission she had been admitted because of the sudden onset of confusion, aphasia, and a generalized seizure with postictal, right-sided hemiparesis. Laboratory data revealed a hematocrit reading of 60%; white blood cell count, 6,300; and