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June 22, 1963


JAMA. 1963;184(12):994-995. doi:10.1001/jama.1963.03700250130050

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Esophageal Stenosis Caused by Thrush.  —L. K. L. Beck (Z Laryng Rhinol Otol41:348, 1962) emphasized that the thrush fungus (Candida albicans, Monilia albicans, Oidium albicans) can often be demonstrated on skin and mucous membrane as a harmless saprophyte. In general debility of the host organism, in local alterations of skin and mucous membrane surface, and in changes of the physiological antagonism between bacteria and fungi, the behavior of the thrush fungus may change and it may become parasitic. From the "latent thrush microbism" (Schürmann) a disease develops, a thrush mycosis. This condition has been on the increase in the last few years, possibly due to the increasing application of antibiotics. Mucosal thrush affects mostly the oral cavity, but spreads also to nose, hypopharynx, larynx, bronchi, lungs, esophagus, and intestines. Metastasation of parenchymatous organs, endocardium and myocardium, or brain becomes possible by infiltration of the blood stream. In the

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