Studies of an epidemic of acute respiratory disease and pneumonia in September through November, 1961, indicated a high degree of association of Type 4 adenovirus with both diseases. Incidence of the diseases was positively correlated with the number of Naval recruits entering training. Routine injection of nonrespiratory-disease vaccines accentuated the incidence, whereas penicillin prophylaxis did not. The pneumonia rate was highest among recruits from the northern US, but was not related to previous urban or rural residence. Clinically and epidemiologically the pneumonia was similar to that reported previously as having affected military recruits in the US and the United Kingdom.
Miller LF, Rytel M, Pierce WE, Rosenbaum MJ. Epidemiology of Nonbacterial Pneumonia Among Naval Recruits. JAMA. 1963;185(2):92–99. doi:10.1001/jama.1963.03060020052021
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