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August 31, 1963

Understanding the Rejection Mechanism Key to Successful TransplantationWhile the rejection process cannot be prevented entirely, its effects can be suppressed, delayed, and reversed

JAMA. 1963;185(9):28-30. doi:10.1001/jama.1963.03060090006003

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Abstract

Nine years ago the first successful renal transplantation between identical twins was reported by a group of surgeons at the Peter Bent Brigham Hospital in Boston.

As of Spring, 1963, "a total of at least 176 renal transplantations have been done," according to Drs. Willard E. Goodwin and Donald C. Martin of Los Angeles in a survey of American and European kidney transplantation experiences to date.

"The number probably exceeds 200 by now—although renal transplantation can hardly be considered a routine procedure," according to Dr. Gilbert Hermann, spokesman for a group of Denver physicians investigating organ transplantation. Other members include Drs. T. E. Starzl, T. L. Marchioro, K. N. von Kaulla, R. S. Brittain, J. F. Mueller, T. A. Witten, W. R. Waddell, O. T. Stonington, J. Holmes, M. P. Hutt, and D. T. Talmadge.

This group, which has performed in excess of 25 human kidney transplants, recently reported transplantation

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