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October 12, 1963

Cytological Changes in the Sweat Gland in Hypothyroidism

Author Affiliations

Portland, Ore.

From the Division of Dermatology, University of Oregon Medical School.

JAMA. 1963;186(2):113-115. doi:10.1001/jama.1963.03710020033007

Biopsy specimens have been obtained from the skin of 28 patients with proven or suspected hypothyroidism. Specific cytologic changes were found in the eccrine sweat glands in all patients who were under treatment for less than 4 months and in some patients who had been treated for a year or longer. Skin biopsy may provide a simple and useful method for the diagnosis of hypothyroidism, particularly when conventional tests are impracticable.