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October 26, 1963


JAMA. 1963;186(4):442. doi:10.1001/jama.1963.03710040168026

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As set forth in the preface, this book represents a collection of informal discussions among investigators interested in phenylketonuria. These conversations took place in 1959, during a meeting of the National Conference on Mental Retardation in Portland, Me. Eleven contributors discuss the genetics, biochemistry, clinical picture, pathology, methods of detection, and management of this disease. To this reviewer, the presentation of the biochemistry seems one of the best chapters of the book. Extensive advice is given on the treatment of this condition, including nearly 30 pages dedicated to special diets and recipes for foods and beverages low in phenylalanine.

This is an excellent work on phenylketonuria, written in a clear, concise, and readable manner. The book is well printed on excellent paper and is highly recommended to all physicians, especially pediatricians, interested in this metabolic disorder which is constantly taking on more importance.

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