For the relief of asthma an almost countless number of drugs have been suggested and tried. It is not my purpose even to enumerate these, but to call attention to those that are to day most frequently employed with success and to those with which I have had personal expererience. Treatment of asthma is prophylactic and also is addressed to the immediate relief of the dyspnœa. In order to understand the mode of action of drugs in asthma, it is necessary to keep in mind its causes and the mechanisms within the body that are called into play in producing the phenomena of the disease. It is true that the bronchial tubes are congested during the dyspnœic attacks, but it is not probable that this is the cause of the difficulty of breathing. A true spasm of the bronchioles constitutes the essential change. This spasm is produced by contraction of
DAVIS NS. THE TREATMENT OF ASTHMA. Portion of a Lecture delivered in the Regular Course of 1888-89. JAMA. 1889;XII(21):726–729. doi:10.1001/jama.1889.02400980006001a
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