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May 25, 1889


JAMA. 1889;XII(21):730-737. doi:10.1001/jama.1889.02400980010002

MICRO-ORGANISMS; AND THEIR RELATION TO DISEASE.  Read before the American Academy of Medicine, and approved by the Council for publication.BY SAMUEL N. NELSON, A.M., M.D., OF BOSTON, MASS.SURGEON TO THE SOLDIERS' HOME IN MASSACHUSETTS.The rôle of the microörganisms called bacteria is at present probably occupying the attention of more scientific men than any other subject in modern science. Great numbers of observers are at work on both continents in the solution of the germ theory of disease. Comparatively unknown till within a few years, on account of their very minute size, these microörganisms attracted attention and experimentation chiefly when the improvement of the microscope allowed objects of their size to come within the limits of its powers of observation. At first simply recognized as existing, their persistence and universality demanded question as to what they are, their origin and object.The history of these microörganisms is related